Состояние и особенности функционирования перекисного окисления липидов и антиоксидантной крови у детей разного возраста

Авторы

DOI:

https://doi.org/10.15574/PP.2016.66.101

Ключевые слова:

перекисное окисление липидов, антиоксидантная система крови, дети

Аннотация


В статье освещена проблема перекисного окисления липидов и антиоксидантной системы крови в патогенезе заболеваний у детей. Представлены данные литературы о течении свободнорадикальных реакций перекисного окисления липидов и роль антиоксидантной системы в поддержании гомеостаза организма.

Ключевые слова: перекисное окисление липидов, антиоксидантная система крови, дети.

Библиографические ссылки

Averyanov NI, Velder EA. 2002. Antioksidantnaya zaschita pri gematurii u detey. Rossiyskiy pediatricheskiy zhurnal. 1: 31—33.

Klebanov GI, Teselkin YuO, Babenkova IV i dr. 1999.Antioksidantnaya aktivnost syivorotki krovi. Vestnik Rossiyskoy akademii meditsinskih nauk. Moskva, Meditsina.

Haytovich NV, Chernyishova OV, Burlaka AP, Sidorik EP. 2003. Antioksidantnaya nedostatochnost u detey s vegetativnyimi disfunktsiyami i ee korrektsiya antioksidantnyim kompleksom Tri Vi Plyus. Perinatologiya i pediatriya. 4: 99—103.

Babintseva AH. 2004. Hipoksychna entsefalopatiia peredchasno narodzhenykh ditei: stan antyoksydantnoho zakhystu orhanizmu v rannomu neonatalnomu periodi. Perynatologiya i pediatriya. 1: 12—14.

Baykova VN, Durnov LA, Belkina BM. 1999. Vliyanie beta-karotina na nekotoryie pokazateli sistemyi svobodnoradikalnogo perekisnogo okisleniya lipidov pri kompleksnom lechenii detey s retinoblastomoy. Pediatriya. 3: 94—96.

Boiechko FF, Boiechko LO. 1993. Osnovni biokhimichni poniattia, vyznachennia i terminy. Kyiv: 530.

Davyidov AA, Zhidovinov GI, Adelshina GA i dr. 1998. Vzaimosvyaz intensivnosti svobodnoradikalnogo okisleniya s urovnem bilirubina pri porazhenii gepatobiliarnoy sistemyi. Klinicheskaya laboratornaya diagnostika. 7:

—13.

Vladimirov YuA, Archakov AI. 1972. Perekisnoe okislenie lipidov v biologicheskih membranah. Moskva, Nauka: 252.

Hliebova LP, Melnyk OI, Ababakov VV. 2002. Stan perekysnoho okyslennia lipidiv ta antyoksydantnoi systemy u ditei, khvorykh na revmatoidnyi artryt. Pediatriia, akusherstvo ta hinekolohiia. 6: 58.

Hubskyi YuI. 2000. Biolohichna khimiia. Kyiv-Ternopil: 508.

Dobrianskyi DO. 2000. Perekysne okyslennia lipidiv, antyoksydantnyi zakhyst i leheneve urazhennia u novonarodzhenykh ditei. Pediatriia, akusherstvo ta hinekolohiia. 6: 15—21.

Dubinina EE. 2001. Rol aktivnyih form kisloroda v kachestve signalnyih molekul v metabolizme tkaney pri sostoyaniyah okislitelnogo stressa. Voprosyi meditsinskoy himii. 47;6: 561—581.

Bondar LS, Artemenko SP, Dehonska IV ta in. 2002. Znachennia kharchovoi alerhii, perekysnoho okyslennia lipidiv, antyoksydantnoho zakhystu u formuvanni riznykh variantiv porushennia stanu pidshlunkovoi zalozy u khvorykh z poiednanoiu patolohiieiu orhaniv travlennia. Pediatriia, akusherstvo ta hinekolohiia. 5: 8—10.

Kazimirko VK, Maltsev VI. 2004. Antioksidantnaya sistema i ee funktsionirovanie v organizme cheloveka. Zdorovia Ukrainy. 13—16(98—101), Lypen — Serpen: 34—36.

Karimov IZ. 2005. Okislitelnaya modifikatsiya belkov i perekisnoe okislenie lipidov v razvitii metabolicheskoy intoksikatsii pri patologii (obzornaya statya). Laboratornaya diagnostika. 1: 7—13.

Kurskyi MD, Kucherenko SM. 1993. Biomembranolohiia. Kyiv, Vyshcha shkola: 260.

Kushnirenko SV. 2003. Stan perekysnoho okyslennia lipidiv ta antyoksydantnoi systemy u ditei, khvorykh na khronichnyi piielonefryt. Perynatologiya i pediatriya. 1: 32—35.

Mansurova FH, Mutihova HSh, Olimova SO. 2005. Perekisnoe okislenie lipidov i antioksidantnaya zaschita u bolnyih s hronicheskim gepatitom S. Klinicheskaya meditsina. 5: 39—42.

Nagoev BS, Marzhohoeva MYu. 2004. Soderzhanie malonovogo dialdegida i tseruloplazmina v plazme krovi u bolnyih s pischevyimi toksikoinfektsiyami. Klinicheskaya laboratornaya diagnostika. 7: 16—18.

Odynets YuV, Yarova KK. 2002. Rol i mistse membranostabilizuiuchoi terapii v likuvanni hostroho hlomerulonefrytu u ditei. Pediatriia, akusherstvo ta hinekolohiia. 2: 64.

Osipov AN, Azizova OA, Vladimirov YuA. 1990. Aktivnyie formyi kisloroda i ih rol v organizme. Uspehi biologicheskoy himii. 31: 180—208.

Duka KD, Koreniu OS, Yefanova AO et al. 2002. Osoblyvosti metabolizmu lipidiv u ditei z chastymy respiratornymy zakhvoriuvanniamy. Pediatriia, akusherstvo ta hinekolohiia. 5: 60.

Pohurska SO. 2005. Dysbalans perekysnoho okyslennia lipidiv — systemy antyoksydantnoho zakhystu — yak lanka patohenezu khronichnoho, retsydyvuiuchoho bronkhitu na foni syderopenii u ditei. Sovremennaya pedyatriya. 2(7).

Pochynok TV, Omelchenko LI, Chernyshov VP et al. 1995. Pokaznyky imunitetu, lipidnoho obminu i strukturno-funktsionalnoho stanu klitynnykh membran u ditei, yaki chasto khvoriiut na HRVI. Pediatriia, akusherstvo ta hinekolohiia. 6: 10—14.

Svitailo OA. 2002. Antyoksydantni preparaty v likuvanni ta profilaktytsi alerhichnoho diatezu. Pediatriia, akusherstvo ta hinekolohiia. 6: 63—64.

Svitailo OA. 1999. Stan systemy perekysnoho okyslennia lipidiv ta antyoksydantnoi systemy u ditei z alerhichnym diatezom. Pediatriia, akusherstvo ta hinekolohiia. 6: 16—18.

Snetkova NS. 2004. Vliyanie oksidantnyih protsessov na techenie dermatorespiratornogo sindroma u detey. Vrachebnaya praktika. 5: 23—25.

Tkachenko GM, Skaletska NM. 2009. Stan prooksidantnoYi ta antioksidantnoYi sistem krovI dItey, scho prozhivayut v ekologIchno nespriyatlivomu regIonI. Environment & Health. 3: 23—26.

Fayziev HN, Aliev AA, Iskandarov ShT. 2001. Sostoyanie perekisnogo okisleniya lipidov i antioksidantnoy sistemyi pri vnutribolnichnoy pnevmonii u detey grudnogo vozrasta i printsipyi patogeneticheskoy terapii. Pediatriya. 1: 97.

Fayzulina RA. 2002. Vliyanie mikroelementarnyih narusheniy na sostoyanie perekisnogo okisleniya lipidov pri hronicheskom gastroduodenite u detey. Pediatriya. 3: 44—48.

Shilina NM. 2009. Mehanizmyi antioksidantnoy zaschityi u detey. Voprosyi pitaniya. 78;3.

Kireev RA, Kurmacheva NA, Maryanovskiy AA i dr. 2002. Effektivnost vliyaniya kompleksnyih antigomotoksicheskih preparatov na sostoyanie perekisnogo okisleniya lipidov, antioksidantnuyu zaschitu i uglevodnyiy obmen u detey s insulinozavisimyim saharnyim diabetom. Rossiyskiy pediatricheskiy zhurnal. 2: 52—56.

Bast AG, Halnen GRMM, Doelman C-SA. 1991. Oxidants and antioxidants: state of the art. American J Med. 91: 7—13.

">http://dx.doi.org/10.1016/0002-9343(91)90278-6

Buonocore G, Perrone S, Logini M. 2000. Total hydroperoxide and advanced oxidation protein products in preterm hypoxic babies. Pediatr Res. 47: 221—224. http://dx.doi.org/10.1203/00006450-200002000-00012; PMid:10674350

Caksen H, Cemek M, Dede S. 2004. Brief clinical study: lipid peroxidation and antioxidant status in children with acute purulent meningitis and encephalitis. Int J Neurosci. 114;1: 105—111. http://dx.doi.org/10.1080/00207450490249383; PMid:14660072

Chang TC, Chou WY, Chang GG. 2000. Protein oxidation and turnover. J Biomed Sci. 7;5: 357—363. http://dx.doi.org/10.1007/BF02255811; PMid:10971134

Chevion M, Berenshtein E, Stadtman ER. 2000. Human studies related to protein oxidation: protein carbonyl content as a marker of damage. Free Radic Res. 33: 99—108.

Davies KL. 1987. Protein damage and degradation by oxygen radicals. I. General aspects. J Biol Chem. 262: 9895—9901. PMid:3036875

Dean RT, Hunt JV, Grant AJ. 1991. Free radicals damage in proteins: the influence of the relative localization of radical generation, antioxidants and target proteins. Biol Med. 11;12: 161-168. http://dx.doi.org/10.1016/0891-5849(91)90167-2

Hendrik TH, Assmann RFTA. 1990. Definition of products lipid peroxidations. Med Lab Sci. 47;1: 10—16.

Kastenbauer S, Koedel U, Becker BF. 2002. Oxidative stress in bacterial meningitis in humans. Neurology. 58;2: 167—168. http://dx.doi.org/10.1212/WNL.58.2.186

Kovacs P, Juranek I, Stancovicov T. 1996. Lipid peroxidation during acute stress. Pharmazie. 51: 51—53. PMid:8999436

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